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Sylvie Laquerre Selected Research

GSK 461364A

12/2011Inhibition of Polo-like kinase 1 prevents the growth of metastatic breast cancer cells in the brain.
7/2010Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability.

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Sylvie Laquerre Research Topics

Disease

13Neoplasms (Cancer)
12/2021 - 01/2005
4Lung Neoplasms (Lung Cancer)
09/2019 - 12/2011
4Breast Neoplasms (Breast Cancer)
01/2017 - 01/2009
2Hematologic Neoplasms (Hematological Malignancy)
12/2021 - 03/2012
2Neoplasm Metastasis (Metastasis)
01/2017 - 12/2011
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2021
1Non-Hodgkin Lymphoma (Lymphosarcoma)
12/2021
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
12/2021
1Inflammation (Inflammations)
07/2018
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2017
1Exanthema (Rash)
01/2016
1Colonic Neoplasms (Colon Cancer)
03/2012
1Brain Neoplasms (Brain Tumor)
12/2011
1Melanoma (Melanoma, Malignant)
12/2010
1Tetraploidy
07/2010
1Chromosomal Instability (Chromosome Stability)
07/2010
1Virus Diseases (Viral Diseases)
10/2005

Drug/Important Bio-Agent (IBA)

4amivantamab-vmjwIBA
10/2020 - 01/2016
4Pharmaceutical PreparationsIBA
12/2011 - 10/2005
2Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
09/2019 - 01/2017
2erdafitinibIBA
09/2019 - 01/2017
2ErbB Receptors (EGF Receptor)IBA
11/2017 - 01/2017
2Proteins (Proteins, Gene)FDA Link
01/2017 - 01/2016
2Tyrosine Kinase InhibitorsIBA
01/2017 - 01/2016
2Biomarkers (Surrogate Marker)IBA
03/2012 - 07/2010
2GSK 461364AIBA
12/2011 - 07/2010
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
12/2010 - 01/2009
1JNJ-64619178IBA
12/2021
1RNA Splicing FactorsIBA
12/2021
1compound 21IBA
06/2021
1FucoseIBA
10/2020
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
09/2019
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2018
1CytokinesIBA
07/2018
1Peptides (Polypeptides)IBA
11/2017
1Dasatinib (BMS 354825)FDA Link
11/2017
1Tyrosine (L-Tyrosine)FDA Link
11/2017
1osimertinibIBA
11/2017
1src-Family KinasesIBA
11/2017
1saracatinibIBA
11/2017
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
01/2017
1Phosphotransferases (Kinase)IBA
01/2016
1GSK 1070916IBA
01/2016
1GSK923295IBA
01/2016
1Aurora KinasesIBA
01/2016
1Cytostatic AgentsIBA
03/2012
1trametinibIBA
03/2012
1Messenger RNA (mRNA)IBA
12/2011
1Polo-Like Kinase 1IBA
12/2011
1GSK 461364IBA
12/2011
1Proto-Oncogene Proteins A-rafIBA
12/2010
1Protein Isoforms (Isoforms)IBA
12/2010
1Phenobarbital (Luminal)FDA Link
01/2009
1AerosolsIBA
10/2005
1Cytosine DeaminaseIBA
01/2005

Therapy/Procedure

4Therapeutics
10/2020 - 07/2010
1Drug Therapy (Chemotherapy)
07/2010